Deletion of the murine scavenger receptor CD68

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Deletion of the murine scavenger receptor CD68.

Scavenger receptors (ScRs) are a structurally unrelated family of receptors with the ability to bind modified low density lipoprotein (LDL) as well as a broad range of polyanionic ligands. CD68, whose expression is restricted to mononuclear phagocytes, is a unique ScR family member, owing to its lysosome associated membrane protein (LAMP)-like domain and predominant endosomal distribution. Knoc...

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 2011

ISSN: 0022-2275

DOI: 10.1194/jlr.m015412